Mitochondrial DNA (mitoDNA) deletions have been shown to increase with aging and ischemia and have been suggested to contribute to myocardial dysfunction. The purpose of this study was to determine the prevalence and specificity of mitoDNA deletions in coronary artery bypass patients.
Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School and Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Room 144, 02115, Boston, MA, USA