rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1992-11-2
|
pubmed:databankReference |
|
pubmed:abstractText |
The murine alpha-lactalbumin-encoding gene (m alpha La) was isolated and completely sequenced. The 2.3-kb transcription unit shared a similar organization with that of its counterparts from other species. Sequence comparison for the proximal 5'-flanking region indicated the presence of a consensus motif that occurs in all milk-protein-encoding genes, except the kappa-casein-encoding gene. This may correspond to the binding site for the recently identified mammary-gland-specific factor. The m alpha La gene occurs in a single copy per haploid genome and is specifically expressed in the mammary gland where it is induced during late pregnancy.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0378-1119
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
119
|
pubmed:geneSymbol |
m&agr;La
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
287-92
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1398111-Amino Acid Sequence,
pubmed-meshheading:1398111-Animals,
pubmed-meshheading:1398111-Base Sequence,
pubmed-meshheading:1398111-Blotting, Southern,
pubmed-meshheading:1398111-Cloning, Molecular,
pubmed-meshheading:1398111-DNA,
pubmed-meshheading:1398111-Female,
pubmed-meshheading:1398111-Humans,
pubmed-meshheading:1398111-Lactalbumin,
pubmed-meshheading:1398111-Lactation,
pubmed-meshheading:1398111-Mice,
pubmed-meshheading:1398111-Molecular Sequence Data,
pubmed-meshheading:1398111-Organ Specificity,
pubmed-meshheading:1398111-Pregnancy,
pubmed-meshheading:1398111-Restriction Mapping,
pubmed-meshheading:1398111-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1398111-Species Specificity
|
pubmed:year |
1992
|
pubmed:articleTitle |
Isolation and characterization of the mouse alpha-lactalbumin-encoding gene: interspecies comparison, tissue- and stage-specific expression.
|
pubmed:affiliation |
Laboratoire de Génétique Biochimique, INRA-CRJ, Jouy-en-Josas, France.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|