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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1993-2-1
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pubmed:abstractText |
The evaluation of sleep EEG patterns is mostly accomplished by visual analysis. With modern personal computers however, it is possible to perform signal detection within a reasonable length of time automatically. This paper presents a method for signal processing based on matched filtering. This allows the detection of sleep spindles and K-complexes in a sleep EEG recording with a high degree of accuracy. First the technique is described, and the results of a validation study based on the comparison of visual evaluations and computer analysis are presented. Thereafter, results of an application study are presented. Sleep spindle and K-complex density under the influence of lormetazepam and zopiclone were examined. Under both medications sleep spindle density increased while K-complex density decreased. Computation of Pearson's correlation coefficients demonstrated that the interindividual sleep spindle and K-complex variations under both treatments are highly correlated. The data suggest that lormetazepam and zopiclone, although chemically different, have a similar mode of action and display comparable effects on the sleep EEG.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0302-282X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
100-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1361968-Adult,
pubmed-meshheading:1361968-Aged,
pubmed-meshheading:1361968-Anti-Anxiety Agents,
pubmed-meshheading:1361968-Arousal,
pubmed-meshheading:1361968-Azabicyclo Compounds,
pubmed-meshheading:1361968-Benzodiazepines,
pubmed-meshheading:1361968-Cerebral Cortex,
pubmed-meshheading:1361968-Double-Blind Method,
pubmed-meshheading:1361968-Electroencephalography,
pubmed-meshheading:1361968-Evoked Potentials,
pubmed-meshheading:1361968-Female,
pubmed-meshheading:1361968-Fourier Analysis,
pubmed-meshheading:1361968-Humans,
pubmed-meshheading:1361968-Hypnotics and Sedatives,
pubmed-meshheading:1361968-Lorazepam,
pubmed-meshheading:1361968-Male,
pubmed-meshheading:1361968-Middle Aged,
pubmed-meshheading:1361968-Piperazines,
pubmed-meshheading:1361968-Polysomnography,
pubmed-meshheading:1361968-Signal Processing, Computer-Assisted,
pubmed-meshheading:1361968-Sleep Initiation and Maintenance Disorders
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pubmed:year |
1992
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pubmed:articleTitle |
Pattern recognition by matched filtering: an analysis of sleep spindle and K-complex density under the influence of lormetazepam and zopiclone.
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pubmed:affiliation |
AFB-Parexel, Arzneimittelforschung GmbH, Berlin, FRG.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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