ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression.

Source:http://linkedlifedata.com/resource/pubmed/id/12973835

Cancer 2003 Sep 15 98 6 1123-30

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PMID
12973835