Linked Life Data

12938207

Source:http://linkedlifedata.com/resource/pubmed/id/12938207

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pubmed-article:12938207pubmed:abstractTextThe antigenic and genetic diversity of G glycoprotein from 25 human respiratory viruses (group A) isolated during nine consecutive epidemics (1993-2001) in Montevideo, Uruguay, and 7 strains isolated in Buenos Aires, Argentina, in the same period were analyzed. Genetic variability was evaluated by partial sequence of the G protein gene. Phylogenetic analysis indicated that most Uruguayan and Argentinean group A isolates clustered into three genotypes: GA5, GA2, and GA1. Some strains clustered into the GA3 genotype characterized previously. The antigenic analysis was carried out with a panel of anti-G monoclonal antibodies that recognized conserved and strain-specific epitopes. A close correlation between the antigenic and genetic relatedness of the strains analyzed was observed.lld:pubmed
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pubmed-article:12938207pubmed:copyrightInfoCopyright 2003 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:12938207pubmed:volume71lld:pubmed
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pubmed-article:12938207pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:12938207pubmed:articleTitleAntigenic and genetic variability of human respiratory syncytial viruses (group A) isolated in Uruguay and Argentina: 1993-2001.lld:pubmed
pubmed-article:12938207pubmed:affiliationSección Virología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.lld:pubmed
pubmed-article:12938207pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12938207pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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