rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2003-8-25
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pubmed:databankReference |
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pubmed:abstractText |
The antigenic and genetic diversity of G glycoprotein from 25 human respiratory viruses (group A) isolated during nine consecutive epidemics (1993-2001) in Montevideo, Uruguay, and 7 strains isolated in Buenos Aires, Argentina, in the same period were analyzed. Genetic variability was evaluated by partial sequence of the G protein gene. Phylogenetic analysis indicated that most Uruguayan and Argentinean group A isolates clustered into three genotypes: GA5, GA2, and GA1. Some strains clustered into the GA3 genotype characterized previously. The antigenic analysis was carried out with a panel of anti-G monoclonal antibodies that recognized conserved and strain-specific epitopes. A close correlation between the antigenic and genetic relatedness of the strains analyzed was observed.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0146-6615
|
pubmed:author |
pubmed-author:ArbizaJuanJ,
pubmed-author:BeroisMabelM,
pubmed-author:CarballalGuadalupeG,
pubmed-author:DelfraroAdrianaA,
pubmed-author:FacalLujánL,
pubmed-author:FrabasileSandraS,
pubmed-author:GalianoMónicaM,
pubmed-author:RuchanskyDoraD,
pubmed-author:RussiJoséJ,
pubmed-author:VidelaCristinaC,
pubmed-author:VitureiraNathaliaN,
pubmed-author:de SierraMaría JoséMJ
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pubmed:copyrightInfo |
Copyright 2003 Wiley-Liss, Inc.
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pubmed:issnType |
Print
|
pubmed:volume |
71
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
305-12
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:12938207-Amino Acid Sequence,
pubmed-meshheading:12938207-Antigenic Variation,
pubmed-meshheading:12938207-Antigens, Viral,
pubmed-meshheading:12938207-Argentina,
pubmed-meshheading:12938207-Child, Preschool,
pubmed-meshheading:12938207-Disease Outbreaks,
pubmed-meshheading:12938207-Genetic Variation,
pubmed-meshheading:12938207-Humans,
pubmed-meshheading:12938207-Molecular Sequence Data,
pubmed-meshheading:12938207-Respiratory Syncytial Virus, Human,
pubmed-meshheading:12938207-Respiratory Syncytial Virus Infections,
pubmed-meshheading:12938207-Sequence Analysis, DNA,
pubmed-meshheading:12938207-Uruguay,
pubmed-meshheading:12938207-Viral Proteins
|
pubmed:year |
2003
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pubmed:articleTitle |
Antigenic and genetic variability of human respiratory syncytial viruses (group A) isolated in Uruguay and Argentina: 1993-2001.
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pubmed:affiliation |
Sección Virología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|