Source:http://linkedlifedata.com/resource/pubmed/id/12893195
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-8-1
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pubmed:abstractText |
The fragile histidine triad (FHIT) gene is located at chromosome 3p14.2 and encompasses the common fragile site, FRA3B, which may contribute to chromosome breakage and rearrangement of cancer cells. Aberrant protein expression and inactivation of the FHIT gene have been identified in a variety of precancerous and cancerous lesions. To identify the potential implications of the FHIT gene in the development of cervical carcinoma and explore the clinical importance of change in gene expression, we assessed the level of Fhit protein in precancerous lesions and carcinomas of the cervix.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0090-8258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
331-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12893195-Acid Anhydride Hydrolases,
pubmed-meshheading:12893195-Adult,
pubmed-meshheading:12893195-Aged,
pubmed-meshheading:12893195-Aged, 80 and over,
pubmed-meshheading:12893195-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:12893195-Disease Progression,
pubmed-meshheading:12893195-Female,
pubmed-meshheading:12893195-Humans,
pubmed-meshheading:12893195-Middle Aged,
pubmed-meshheading:12893195-Neoplasm Proteins,
pubmed-meshheading:12893195-Neoplasm Staging,
pubmed-meshheading:12893195-Prognosis,
pubmed-meshheading:12893195-Uterine Cervical Neoplasms
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pubmed:year |
2003
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pubmed:articleTitle |
Reduced Fhit expression in cervical carcinoma: correlation with tumor progression and poor prognosis.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. m002057@ms.skh.org.tw
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pubmed:publicationType |
Journal Article
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