Source:http://linkedlifedata.com/resource/pubmed/id/12831179
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2003-6-30
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pubmed:abstractText |
It is only by developing specially designed injection and detection systems that shear-driven chromatography can become a viable alternative to HPLC. In the present paper, a dedicated zero dead-volume injection procedure is presented with which sample volumes can be injected reproducibly in the required picoliter range. In addition, a transversal detection groove system is designed which should allow to perform on-line UV-VIS absorption measurements with path lengths in the millimeter range, with an acceptable theoretical plate loss (only 20% in a 5 cm long channel) and acting as a nearly perfect wave guide.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0021-9673
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
948
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-34
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pubmed:dateRevised |
2009-1-15
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pubmed:meshHeading |
pubmed-meshheading:12831179-Algorithms,
pubmed-meshheading:12831179-Chemistry, Physical,
pubmed-meshheading:12831179-Chromatography, High Pressure Liquid,
pubmed-meshheading:12831179-Chromatography, Liquid,
pubmed-meshheading:12831179-Diffusion,
pubmed-meshheading:12831179-Physicochemical Phenomena,
pubmed-meshheading:12831179-Spectrophotometry, Ultraviolet
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pubmed:year |
2002
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pubmed:articleTitle |
Shear-flow-based chromatographic separations as an alternative to pressure-driven liquid chromatography.
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pubmed:affiliation |
Vrije Universiteit Brussel, Department of Chemical Engineering, Pleinlaan 2, 1050 Brussels, Belgium. gedesmet@vub.ac.be
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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