Source:http://linkedlifedata.com/resource/pubmed/id/12764694
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2003-5-23
|
| pubmed:abstractText |
We used Wavelet transform (WT) to investigate whether variation in autonomic tone was associated with spontaneous coronary spasm in patients with variant angina by analysis of heart rate variability (HRV). Twenty-one episodes preceding ST-segment elevation were selected under Holter monitoring in 12 men and 3 women with variant angina. HRV indices were calculated at 10 second intervals with the continuous WT, and analyzed within 30 minutes preceding ST-segment elevation. High frequency (HF; 0.15 approximately 2.00 Hz) increased significantly during the 4 minutes prior to ST-segment elevation, low frequency (LF; 0.04 approximately 0.15 Hz) decreased significantly during the period from 10 to 5 minutes and increased significantly during the 2 minutes prior to ST-segment elevation, the LF/HF ratio decreased significantly during the period from 10 to 3 minutes and increased significantly during the 2 minutes prior to ST-segment elevation. The RR interval decreased significantly during the 2 minutes prior to ST-segment elevation. These results suggest that the acute variation in autonomic tone was associated with spontaneous coronary spasm in patients with variant angina. A reduction in sympathetic activity, then enhancement of vagal activity may play a key role in triggering the spontaneous coronary spasm, and the secondary activation of sympathetic activity may worsen the coronary spasm resulting in the attack.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0022-0736
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
36
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
117-24
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| pubmed:dateRevised |
2009-11-11
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| pubmed:meshHeading |
pubmed-meshheading:12764694-Adult,
pubmed-meshheading:12764694-Aged,
pubmed-meshheading:12764694-Analysis of Variance,
pubmed-meshheading:12764694-Angina Pectoris, Variant,
pubmed-meshheading:12764694-Autonomic Nervous System,
pubmed-meshheading:12764694-Coronary Vasospasm,
pubmed-meshheading:12764694-Electrocardiography, Ambulatory,
pubmed-meshheading:12764694-Female,
pubmed-meshheading:12764694-Heart Rate,
pubmed-meshheading:12764694-Humans,
pubmed-meshheading:12764694-Male,
pubmed-meshheading:12764694-Middle Aged
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Wavelet transform analysis of heart rate variability to assess the autonomic changes associated with spontaneous coronary spasm of variant angina.
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| pubmed:affiliation |
Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. bihuatan@hyo-med.ac.jp
|
| pubmed:publicationType |
Journal Article
|