Linked Life Data

1266659

Source:http://linkedlifedata.com/resource/pubmed/id/1266659

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1976-7-6
pubmed:abstractText
Toxicity of contrast media that are ionized iodobenzoic acids or their derivatives is highly correlated with lipid solubility, as measured by the octanol/water partition coefficient. New contrast media have been designed with lower lipid solubility than media in current use, taking into account the additive-constitutive nature of the partition coefficient of an organic compound. If these contrast media are chemically stable, they should also be less toxic. It remains to be tested whether the relation between clinical toxicity and lipid solubility applies to non-ionized contrast media as well.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0567-8056
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-92
pubmed:dateRevised
2011-10-25
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Contrast media: quantitative criteria for designing compounds with low toxicity.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.