|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002594,
umls-concept:C0005910,
umls-concept:C0023688,
umls-concept:C0030705,
umls-concept:C0031928,
umls-concept:C0289313,
umls-concept:C0920563,
umls-concept:C1274040,
umls-concept:C1280500,
umls-concept:C2711227,
umls-concept:C2827738
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2003-3-28
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|
pubmed:abstractText |
Hyperinsulinemia may cause hepatic steatosis and non-alcoholic steatohepatitis (NASH). The aims of this pilot study were to examine the safety of using the insulin-sensitizing peroxisomal proliferator activated receptor (PPAR) gamma ligand rosiglitazone in patients with NASH and determine whether improved insulin sensitivity correlates with improved fatty liver.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0168-8278
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
38
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
434-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12663234-Adult,
pubmed-meshheading:12663234-Aged,
pubmed-meshheading:12663234-Alanine Transaminase,
pubmed-meshheading:12663234-Aspartate Aminotransferases,
pubmed-meshheading:12663234-Body Weight,
pubmed-meshheading:12663234-Fatty Liver,
pubmed-meshheading:12663234-Female,
pubmed-meshheading:12663234-Glucose Tolerance Test,
pubmed-meshheading:12663234-Humans,
pubmed-meshheading:12663234-Hypoglycemic Agents,
pubmed-meshheading:12663234-Insulin Resistance,
pubmed-meshheading:12663234-Ligands,
pubmed-meshheading:12663234-Male,
pubmed-meshheading:12663234-Middle Aged,
pubmed-meshheading:12663234-Patient Dropouts,
pubmed-meshheading:12663234-Pilot Projects,
pubmed-meshheading:12663234-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:12663234-Thiazolidinediones,
pubmed-meshheading:12663234-Transcription Factors,
pubmed-meshheading:12663234-Treatment Outcome
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis.
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|
pubmed:affiliation |
Department of Internal Medicine, Saint Louis University Liver Center, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, MO 63110, USA. tetriba@slu.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
