12633670

Source:http://linkedlifedata.com/resource/pubmed/id/12633670

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0851285, umls-concept:C1515432
pubmed:issue	2
pubmed:dateCreated	2003-3-13
pubmed:abstractText	T cell antigen receptor-induced signals are required for normal T cell development and function. Recent studies have investigated the mechanism(s) by which signals of different strengths are converted into distinct cellular fates during thymocyte development. These studies indicate the importance of the strength and duration of signals activated through PLC and PKC pathways in shaping the mature TCR repertoire.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8900118
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0952-7915
pubmed:author	pubmed-author:ChanAndrew CAC, pubmed-author:LovePaul EPE
pubmed:issnType	Print
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	199-203
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:12633670-Animals, pubmed-meshheading:12633670-Humans, pubmed-meshheading:12633670-Receptors, Antigen, T-Cell, pubmed-meshheading:12633670-Signal Transduction, pubmed-meshheading:12633670-T-Lymphocytes, pubmed-meshheading:12633670-Thymus Gland
pubmed:year	2003
pubmed:articleTitle	Regulation of thymocyte development: only the meek survive.
pubmed:affiliation	Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. pel@helix.nih.gov
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Review