rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2003-3-12
|
pubmed:abstractText |
Management of secondary hyperparathyroidism has included the use of active vitamin D or vitamin D analogs for the suppression of parathyroid hormone (PTH) secretion. Although, these agents are effective, therapy is frequently limited by hypercalcemia, hyperphosphatemia, and/or elevations in the calcium-phosphorus (Ca x P) product. In clinical studies, paricalcitol was shown to be effective at reducing PTH concentrations without causing significant hypercalcemia or hyperphosphatemia as compared to placebo. A comparative study was undertaken in order to determine whether paricalcitol provides a therapeutic advantage to calcitriol.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0085-2538
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
63
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1483-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12631365-Adult,
pubmed-meshheading:12631365-Aged,
pubmed-meshheading:12631365-Calcitriol,
pubmed-meshheading:12631365-Calcium Channel Agonists,
pubmed-meshheading:12631365-Ergocalciferols,
pubmed-meshheading:12631365-Female,
pubmed-meshheading:12631365-Humans,
pubmed-meshheading:12631365-Hypercalcemia,
pubmed-meshheading:12631365-Hyperparathyroidism, Secondary,
pubmed-meshheading:12631365-Incidence,
pubmed-meshheading:12631365-Male,
pubmed-meshheading:12631365-Middle Aged,
pubmed-meshheading:12631365-Parathyroid Hormone
|
pubmed:year |
2003
|
pubmed:articleTitle |
Paricalcitol versus calcitriol in the treatment of secondary hyperparathyroidism.
|
pubmed:affiliation |
Division of Nephrology/Hypertension and Department of Medicine, Northwestern University Feinberg School of Medicine, Evanston, Illinois 60201, USA. ssprague@northwestern.edu
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
|