Source:http://linkedlifedata.com/resource/pubmed/id/12615616
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2003-4-25
|
| pubmed:abstractText |
To determine whether acute respiratory distress syndrome (ARDS) complicating bacteremic sepsis independently affects mortality in critically ill patients, we conducted a 3-year retrospective cohort study in a surgical intensive care unit. We included all consecutive patients with blood culture-positive sepsis and measured organ dysfunctions and mortality. Among 4,530 admissions, 196 cases of bacteremic sepsis were recorded. ARDS occurred in 31 (16%) of these patients. The case fatality rate was 58% in patients with ARDS compared with 31% in patients without ARDS. Using Cox proportional hazards regression with time-dependent variables, the unadjusted hazard ratio for death was 1.8 (95% confidence interval [CI], 1.0-3.2). After adjusting for comorbid factors that were present before the onset of sepsis, the hazard ratio was 2.2 (95% CI, 1.2-3.9). After further adjustment was made for nonpulmonary organ dysfunctions and microbiologic factors that were independently associated with mortality, the adjusted hazard ratio for ARDS was 0.6 (95% CI, 0.3-1.2). Among critically ill surgical patients, ARDS complicating bacteremic sepsis remains common, but it is not independently associated with short-term mortality, after adjusting for severity of illness and nonpulmonary organ dysfunctions evolving after the onset of sepsis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
1073-449X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
167
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1210-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:12615616-APACHE,
pubmed-meshheading:12615616-Acute Disease,
pubmed-meshheading:12615616-Aged,
pubmed-meshheading:12615616-Analysis of Variance,
pubmed-meshheading:12615616-Bacteremia,
pubmed-meshheading:12615616-Cause of Death,
pubmed-meshheading:12615616-Comorbidity,
pubmed-meshheading:12615616-Critical Illness,
pubmed-meshheading:12615616-Female,
pubmed-meshheading:12615616-Hospital Mortality,
pubmed-meshheading:12615616-Hospitals, University,
pubmed-meshheading:12615616-Humans,
pubmed-meshheading:12615616-Length of Stay,
pubmed-meshheading:12615616-Male,
pubmed-meshheading:12615616-Middle Aged,
pubmed-meshheading:12615616-Prognosis,
pubmed-meshheading:12615616-Proportional Hazards Models,
pubmed-meshheading:12615616-Respiratory Distress Syndrome, Adult,
pubmed-meshheading:12615616-Retrospective Studies,
pubmed-meshheading:12615616-Risk Factors,
pubmed-meshheading:12615616-Severity of Illness Index,
pubmed-meshheading:12615616-Survival Analysis,
pubmed-meshheading:12615616-Switzerland
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Acute respiratory distress syndrome after bacteremic sepsis does not increase mortality.
|
| pubmed:affiliation |
Department of Medicine, Infection Control Program, University of Geneva Hospitals, 1211 Geneva 14, Switzerland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|