Source:http://linkedlifedata.com/resource/pubmed/id/12470879
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-12-9
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pubmed:abstractText |
We examined the effects of discrete, bilateral excitotoxic lesions of the central or basolateral nucleus of the amygdala on naloxone-precipitated withdrawal-induced conditioned place aversion in morphine-dependent rats. Lesions of the central nucleus significantly attenuated the conditioned place aversion, while lesions of the basolateral nucleus had little effect. These results suggest that the central nucleus of the amygdala, rather than the basolateral nucleus, plays a crucial role in the negative affective component of morphine abstinence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2002 Elsevier Science B.V.
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
958
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
423-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12470879-Amygdala,
pubmed-meshheading:12470879-Animals,
pubmed-meshheading:12470879-Conditioning (Psychology),
pubmed-meshheading:12470879-Excitatory Amino Acid Agonists,
pubmed-meshheading:12470879-Male,
pubmed-meshheading:12470879-Morphine Dependence,
pubmed-meshheading:12470879-Naloxone,
pubmed-meshheading:12470879-Rats,
pubmed-meshheading:12470879-Rats, Sprague-Dawley,
pubmed-meshheading:12470879-Substance Withdrawal Syndrome
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pubmed:year |
2002
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pubmed:articleTitle |
Effects of excitotoxic lesions of the central or basolateral nucleus of the amygdala on naloxone-precipitated withdrawal-induced conditioned place aversion in morphine-dependent rats.
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pubmed:affiliation |
Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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