Source:http://linkedlifedata.com/resource/pubmed/id/12170121
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2002-8-9
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pubmed:abstractText |
Many studies have reported apparent associations between platelet monoamine oxidase (MAO) activity and susceptibility to alcoholism and other psychiatric conditions. Alcohol-dependent individuals generally exhibit lower platelet MAO activity compared with controls, and on this basis, platelet MAO has been proposed as a potential genetic marker for predisposition to alcoholism. However, several lines of evidence also suggest that MAO activity is reduced in both the brain and platelets of smokers. Many alcohol-dependent individuals are also tobacco users, and few studies have attempted to dissociate the effect of alcohol and tobacco use on MAO activity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0145-6008
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1105-13
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12170121-Adolescent,
pubmed-meshheading:12170121-Adult,
pubmed-meshheading:12170121-Affinity Labels,
pubmed-meshheading:12170121-Aged,
pubmed-meshheading:12170121-Alcoholism,
pubmed-meshheading:12170121-Analysis of Variance,
pubmed-meshheading:12170121-Enzyme Activation,
pubmed-meshheading:12170121-Female,
pubmed-meshheading:12170121-Humans,
pubmed-meshheading:12170121-Male,
pubmed-meshheading:12170121-Middle Aged,
pubmed-meshheading:12170121-Monoamine Oxidase,
pubmed-meshheading:12170121-Protein Binding,
pubmed-meshheading:12170121-Regression Analysis,
pubmed-meshheading:12170121-Sex Factors,
pubmed-meshheading:12170121-Smoking,
pubmed-meshheading:12170121-Statistics, Nonparametric
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pubmed:year |
2002
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pubmed:articleTitle |
Relationships between effects of smoking, gender, and alcohol dependence on platelet monoamine oxidase-B: activity, affinity labeling, and protein measurements.
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pubmed:affiliation |
Lohocla Research Corporation, Denver, Colorado, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study
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