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rdf:type |
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lifeskim:mentions |
umls-concept:C0003062,
umls-concept:C0020672,
umls-concept:C0021270,
umls-concept:C0031928,
umls-concept:C0034656,
umls-concept:C0235820,
umls-concept:C0302523,
umls-concept:C0700325,
umls-concept:C1515273,
umls-concept:C1527178,
umls-concept:C1705313,
umls-concept:C2587213
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pubmed:issue |
2 Pt 1
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pubmed:dateCreated |
2002-8-7
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pubmed:abstractText |
Modest reduction in brain temperature is a promising therapy to reduce brain damage after neonatal encephalopathy as a result of acute perinatal asphyxia. The efficacy of modest hypothermia may in part be dependent on the stability of the desired brain temperature. The objective of this study was 1) to evaluate in newborn animals a commercially available cooling system (Blanketrol II Hyperthermia-Hypothermia system) to control brain temperature during whole-body hypothermia and 2) to use the results of the animal experiments to perform a pilot study evaluating the feasibility of whole-body hypothermia as a neuroprotective therapy for newborns with encephalopathy at birth.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/U01 HD36790,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21364,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21373,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21385,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21397,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21415,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27851,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27853,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27856,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27871,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27880,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27881,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27904,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD34167,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD34216,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD40689
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1098-4275
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pubmed:author |
pubmed-author:BauerCharles RCR,
pubmed-author:CarloWaldemar AWA,
pubmed-author:DonovanEdward FEF,
pubmed-author:EhrenkranzRichard ARA,
pubmed-author:FanaroffAvroy AAA,
pubmed-author:KoronesSheldon BSB,
pubmed-author:LaptookAbbotA,
pubmed-author:LemonsJames AJA,
pubmed-author:McDonaldScottS,
pubmed-author:OhWilliamW,
pubmed-author:PapileLu-AnnLA,
pubmed-author:PooleKennethK,
pubmed-author:ShankaranSeethaS,
pubmed-author:StarkAnn RAR,
pubmed-author:StevensonDavid KDK,
pubmed-author:StollBarbara JBJ,
pubmed-author:TysonJon EJE,
pubmed-author:WrightLinda LLL
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pubmed:issnType |
Electronic
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-85
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12165594-Animals,
pubmed-meshheading:12165594-Animals, Newborn,
pubmed-meshheading:12165594-Asphyxia Neonatorum,
pubmed-meshheading:12165594-Brain Diseases,
pubmed-meshheading:12165594-Feasibility Studies,
pubmed-meshheading:12165594-Humans,
pubmed-meshheading:12165594-Hypothermia, Induced,
pubmed-meshheading:12165594-Infant, Newborn,
pubmed-meshheading:12165594-Models, Animal,
pubmed-meshheading:12165594-Pilot Projects,
pubmed-meshheading:12165594-Swine
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pubmed:year |
2002
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pubmed:articleTitle |
Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants.
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pubmed:affiliation |
Wayne State University, Detroit, Michigan, USA. s_shankaran@wayne.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Evaluation Studies
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