Linked Life Data

12122612

Source:http://linkedlifedata.com/resource/pubmed/id/12122612

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-7-17
pubmed:abstractText
Increased QT interval and QT dispersion have been associated with increased mortality in a variety of cardiovascular disorders including heart failure. However, the biological correlates of these abnormalities are not clear. QTc and QTd were measured in an automated fashion from digitized electrocardiograms in 2,265 patients with an LV ejection fraction </=40% and were related to clinical, electrocardiographic, and echocardiographic variables. The QTc interval increased with increasing age (P =.0003), heart rate (P <.0001), LV dimensions (P <.0001), left atrial diameter (P <.0001), estimated right atrial pressure (P <.0001), QRS duration (P <.0001), bundle branch blocks (P <.0001) and degree of mitral and tricuspid regurgitation (P <.0001) and decreasing LV ejection fraction (P <.0001) QT dispersion increased with increasing LV isovolumic relaxation time (P =.004) and QTc (P <.0001) and decreased with faster heart rate (P <.0001) and higher right atrial pressure (P =.0007). The biological relationships of QTc and QTd warrant further investigations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-0736
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
223-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Biological correlates of QT interval and QT dispersion in 2,265 patients with left ventricular ejection fraction < or =40%.
pubmed:affiliation
Department of Cardiology, Loma Linda University and VA Medical Center, CA 92354, USA. ramdaspai@yahoo.com
pubmed:publicationType
Journal Article