rdf:type |
|
lifeskim:mentions |
umls-concept:C0021747,
umls-concept:C0080103,
umls-concept:C0205147,
umls-concept:C0376705,
umls-concept:C0525038,
umls-concept:C0871261,
umls-concept:C1148363,
umls-concept:C1533728,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
4
|
pubmed:dateCreated |
2002-5-10
|
pubmed:abstractText |
The interferon sensitivity-determining region (ISDR) in nonstructural region 5A (NS5A) of hepatitis C virus genotype 1b has been reported to correlate with response to interferon therapy and viral load. Recently the correlation between NS5A and response to interferon in genotype 2a was also reported. We examined the region of genotypes 2a and 2b corresponding to the ISDR of genotype lb to elucidate its correlation with response to interferon and viral load.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0002-9270
|
pubmed:author |
pubmed-author:HattoriMasakiM,
pubmed-author:IshigamiMasatoshiM,
pubmed-author:ItoHiroshiH,
pubmed-author:KakumuShinichiS,
pubmed-author:KobayashiMakotoM,
pubmed-author:MuraseKenichiK,
pubmed-author:TakagiKenjiK,
pubmed-author:UkaiKojiK,
pubmed-author:WatanabeKazumasaK,
pubmed-author:YanoMotoyoshiM,
pubmed-author:YoshiokaKentaroK
|
pubmed:issnType |
Print
|
pubmed:volume |
97
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
988-98
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:12003437-5' Flanking Region,
pubmed-meshheading:12003437-Adult,
pubmed-meshheading:12003437-Amino Acid Substitution,
pubmed-meshheading:12003437-Antiviral Agents,
pubmed-meshheading:12003437-Female,
pubmed-meshheading:12003437-Genotype,
pubmed-meshheading:12003437-Hepacivirus,
pubmed-meshheading:12003437-Hepatitis C,
pubmed-meshheading:12003437-Humans,
pubmed-meshheading:12003437-Interferons,
pubmed-meshheading:12003437-Male,
pubmed-meshheading:12003437-Middle Aged,
pubmed-meshheading:12003437-Retrospective Studies,
pubmed-meshheading:12003437-Viral Load,
pubmed-meshheading:12003437-Viral Nonstructural Proteins
|
pubmed:year |
2002
|
pubmed:articleTitle |
Amino acid substitutions in the nonstructural region 5A of hepatitis C virus genotypes 2a and 2b and its relation to viral load and response to interferon.
|
pubmed:affiliation |
Third Department of Internal Medicine, Nagoya University School of Medicine, Japan.
|
pubmed:publicationType |
Journal Article
|