12002128

Source:http://linkedlifedata.com/resource/pubmed/id/12002128

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0040300, umls-concept:C0443199, umls-concept:C0871935, umls-concept:C1512571, umls-concept:C1880156, umls-concept:C1947950, umls-concept:C2713544
pubmed:issue	2
pubmed:dateCreated	2002-5-10
pubmed:abstractText	A comprehensive theory, herein named the Differential Interfacial Tension Hypothesis for the self-rearrangement of embryonic cells and tissues is presented. These rearrangements include sorting, mixing and formation of checkerboard patterns in heterotypic aggregates of embryonic cells, and total or partial engulfment, separation and dissociation of tissues. This broadly-based theory accounts for the action of all currently known cytoskeletal components and cell adhesion mechanisms. The theory is used to derive conditions for the cell and tissue rearrangements named above. Finite element-based computer simulations involving two or more cell types confirm these conditions.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7909584
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0148-0731
pubmed:author	pubmed-author:BrodlandG WayneGW
pubmed:issnType	Print
pubmed:volume	124
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	188-97
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:12002128-Cell Adhesion, pubmed-meshheading:12002128-Cell Aggregation, pubmed-meshheading:12002128-Cell Size, pubmed-meshheading:12002128-Computer Simulation, pubmed-meshheading:12002128-Finite Element Analysis, pubmed-meshheading:12002128-Intercellular Junctions, pubmed-meshheading:12002128-Models, Biological, pubmed-meshheading:12002128-Morphogenesis, pubmed-meshheading:12002128-Movement, pubmed-meshheading:12002128-Phagocytosis, pubmed-meshheading:12002128-Rheology, pubmed-meshheading:12002128-Sensitivity and Specificity, pubmed-meshheading:12002128-Stem Cells, pubmed-meshheading:12002128-Stress, Mechanical, pubmed-meshheading:12002128-Surface Tension
pubmed:year	2002
pubmed:articleTitle	The Differential Interfacial Tension Hypothesis (DITH): a comprehensive theory for the self-rearrangement of embryonic cells and tissues.
pubmed:affiliation	Department of Civil Engineering, University of Waterloo, ON, Canada. brodland@uwaterloo.ca
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't