Source:http://linkedlifedata.com/resource/pubmed/id/11979022
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2002-4-29
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pubmed:abstractText |
Current data on rapid and long-acting insulin analogues in the paediatric age group is limited. While several studies indicate a benefit in reducing hypoglycaemia, particularly at night, with rapid or long-acting insulin analogue treatment, the effect on long-term glycaemic control remains controversial. The continuous glucose monitoring system offers a new option for tailoring treatment with insulin analogues to achieve optimal glycaemia. In 29 adolescents with diabetes this approach confirmed the non-inferiority of postprandial rapid-acting analogue administration compared to preprandial regular insulin, but revealed significant mealtime differences, with increased analogue requirement at breakfast and dinner. Although rapid- and long-acting insulin analogues may offer potential benefits for problems frequently encountered in paediatric diabetology, their value for the individual child still has to be tested in long-term observations in daily clinical practice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-0163
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2002 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
57 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
46-53
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11979022-Blood Glucose,
pubmed-meshheading:11979022-Child,
pubmed-meshheading:11979022-Diabetes Mellitus, Type 1,
pubmed-meshheading:11979022-Drug Combinations,
pubmed-meshheading:11979022-Humans,
pubmed-meshheading:11979022-Infusion Pumps,
pubmed-meshheading:11979022-Insulin,
pubmed-meshheading:11979022-Safety
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pubmed:year |
2002
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pubmed:articleTitle |
Experience with insulin analogues in children.
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pubmed:affiliation |
Diabetes-Zentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Hannover, Germany. danne@hka.de
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pubmed:publicationType |
Journal Article,
Review
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