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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-3-28
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pubmed:abstractText |
The erythropoietin-producing hepatoma amplified sequence (Eph) family is the largest subfamily of receptor tyrosine kinases (RTKs). The Ephs (receptors) bind to specific cell-bound ligands, called ephrins. The binding of this ligand-receptor system is dependent on cell-cell interactions. The ephrin-Eph system is important in embryologic development and differentiation of the nervous and vascular systems. In the current study, the authors hypothesized that ephrins may play a role in the growth and development of colon carcinoma and may be expressed differentially in normal and malignant colonic tissues.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Ephrin-B2,
http://linkedlifedata.com/resource/pubmed/chemical/Ephrin-B3,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, EphB4,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Eph Family,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 American Cancer Society. DOI 10.1002/cncr.10122
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
934-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11920461-Blotting, Northern,
pubmed-meshheading:11920461-Carcinoma,
pubmed-meshheading:11920461-Cell Transformation, Neoplastic,
pubmed-meshheading:11920461-Colonic Neoplasms,
pubmed-meshheading:11920461-DNA Primers,
pubmed-meshheading:11920461-Disease Progression,
pubmed-meshheading:11920461-Ephrin-B2,
pubmed-meshheading:11920461-Ephrin-B3,
pubmed-meshheading:11920461-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11920461-Humans,
pubmed-meshheading:11920461-Immunohistochemistry,
pubmed-meshheading:11920461-Membrane Proteins,
pubmed-meshheading:11920461-RNA, Messenger,
pubmed-meshheading:11920461-Receptor, EphB4,
pubmed-meshheading:11920461-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:11920461-Receptors, Eph Family,
pubmed-meshheading:11920461-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11920461-Tumor Cells, Cultured,
pubmed-meshheading:11920461-Tumor Markers, Biological
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pubmed:year |
2002
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pubmed:articleTitle |
Coexpression of ephrin-Bs and their receptors in colon carcinoma.
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pubmed:affiliation |
Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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