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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-2-28
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pubmed:abstractText |
Neuroendocrine (NE) cells are androgen-independent cells and secrete growth-modulating peptide hormones via a regulated secretory pathway (RSP). We studied NE differentiation after long-term androgen withdrawal in the androgen-dependent human prostate cancer xenograft PC-310.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androgens,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Chromogranin A,
http://linkedlifedata.com/resource/pubmed/chemical/Chromogranins,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances,
http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases,
http://linkedlifedata.com/resource/pubmed/chemical/Multienzyme Complexes,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Prostate-Specific Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Androgen,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/peptidylglycine monooxygenase
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11870798-Androgens,
pubmed-meshheading:11870798-Animals,
pubmed-meshheading:11870798-Antigens, Nuclear,
pubmed-meshheading:11870798-Blotting, Western,
pubmed-meshheading:11870798-Cell Cycle Proteins,
pubmed-meshheading:11870798-Cell Differentiation,
pubmed-meshheading:11870798-Chromogranin A,
pubmed-meshheading:11870798-Chromogranins,
pubmed-meshheading:11870798-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:11870798-Growth Substances,
pubmed-meshheading:11870798-Humans,
pubmed-meshheading:11870798-Immunohistochemistry,
pubmed-meshheading:11870798-Male,
pubmed-meshheading:11870798-Mice,
pubmed-meshheading:11870798-Mice, Nude,
pubmed-meshheading:11870798-Mixed Function Oxygenases,
pubmed-meshheading:11870798-Multienzyme Complexes,
pubmed-meshheading:11870798-Neurosecretory Systems,
pubmed-meshheading:11870798-Nuclear Proteins,
pubmed-meshheading:11870798-Orchiectomy,
pubmed-meshheading:11870798-Prostate-Specific Antigen,
pubmed-meshheading:11870798-Prostatic Neoplasms,
pubmed-meshheading:11870798-Protein Biosynthesis,
pubmed-meshheading:11870798-Proteins,
pubmed-meshheading:11870798-Receptors, Androgen,
pubmed-meshheading:11870798-Tumor Cells, Cultured,
pubmed-meshheading:11870798-Tumor Suppressor Proteins
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pubmed:year |
2002
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pubmed:articleTitle |
Different profiles of neuroendocrine cell differentiation evolve in the PC-310 human prostate cancer model during long-term androgen deprivation.
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pubmed:affiliation |
Department of Experimental Urology, Josephine Nefkens Institute, Erasmus University, Rotterdam, Netherlands. jongsma@nki.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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