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pubmed-article:11828291pubmed:abstractTextAlthough we have previously shown that inhibition of nuclear factor kappaB sensitizes non-small cell lung cancer cells to chemotherapy-mediated cell death, the apoptotic pathways mediating this process are unknown. The purpose of this study was to determine whether chemosensitivity after the inhibition of nuclear factor kappaB in non-small cell lung cancer cells is a mitochondrial and caspase-mediated process and whether it is dependent on nuclear factor kappaB transcriptional activity.lld:pubmed
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pubmed-article:11828291pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:11828291pubmed:articleTitleInhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation.lld:pubmed
pubmed-article:11828291pubmed:affiliationDepartment of Surgery, The University of Virginia, Charlottesville, VA 22908-0679, USA. djones@virginia.edulld:pubmed
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