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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1975-12-28
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pubmed:abstractText |
Attempts were made to isolate and identify the unit chemical structure essential for manifestation of the immunoadjuvant activities characteristic of bacterial cell walls. The N-acetylmuramyl-peptide subunit monomers, Nalpha-(N-acetylmuramyl-L-alanyl-D-isoglutaminyl)-Nepsilon-(glycylglycyl)-L-lysyl-D-alanine from the cell walls of Staphylococcus aureus (FDA 209P) and N-acetylmuramyl-L-alanyl-D-isoglutaminyl-meso-diaminopimelic acid and/or N-acetylmuramyl-L-alanyl-D-isoglutaminyl-meso-diaminopimelyl-D-alanine from those of Lactobacillus plantarum (ATCC 8014), were shown to be unit chemical entities with definite adjuvant activity both in stimulation of antibody production and in induction of delayed-type hypersensitivity to ovalbumin when administered to guinea-pigs as water-in-oil emulsions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0006-2324
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
93-103
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1180873-Adjuvants, Immunologic,
pubmed-meshheading:1180873-Animals,
pubmed-meshheading:1180873-Antibody Formation,
pubmed-meshheading:1180873-Cell Wall,
pubmed-meshheading:1180873-Guinea Pigs,
pubmed-meshheading:1180873-Hypersensitivity, Delayed,
pubmed-meshheading:1180873-Lactobacillus,
pubmed-meshheading:1180873-Ovalbumin,
pubmed-meshheading:1180873-Peptidoglycan,
pubmed-meshheading:1180873-Staphylococcus aureus
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pubmed:year |
1975
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pubmed:articleTitle |
Immunoadjuvant activities of peptidoglycan subunits from the cell walls of Staphyloccus aureus and Lactobacillus plantarum.
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pubmed:publicationType |
Journal Article
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