Source:http://linkedlifedata.com/resource/pubmed/id/11760158
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2001-12-10
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pubmed:abstractText |
The avidity indices of Borrelia burgdorferi-specific IgG antibodies were estimated using ELISA in sera from patients with different stages of Lyme disease. In addition, sera from healthy students with proof of borrelial-specific IgG antibodies from standard serology were tested. Low avidity indices were detected predominantly in sera from patients with early-stage Lyme disease [erythema migrans (EM); n = 25]. High avidity indices were found in healthy students (n = 72) and in most of the patients with neuroborreliosis (NB; n = 44) and chronic late-stage Lyme disease [acrodermatitis chronica atrophicans (ACA); n = 36]. In conclusion, early-stage Lyme disease (EM) could be differentiated from advanced and chronic stages (NB, ACA) and from "seropositive" healthy persons using avidity determination in the majority of patients in this study.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
809-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11760158-Antibody Affinity,
pubmed-meshheading:11760158-Antigens, Bacterial,
pubmed-meshheading:11760158-Borrelia burgdorferi,
pubmed-meshheading:11760158-Case-Control Studies,
pubmed-meshheading:11760158-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11760158-Humans,
pubmed-meshheading:11760158-Immunoglobulin G,
pubmed-meshheading:11760158-Lyme Disease,
pubmed-meshheading:11760158-Lyme Neuroborreliosis,
pubmed-meshheading:11760158-Severity of Illness Index
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pubmed:year |
2001
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pubmed:articleTitle |
Avidity determination of Borrelia burgdorferi-specific IgG antibodies in Lyme disease.
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pubmed:affiliation |
Department of Neurology, Albert Ludwig University, Freiburg, Germany. rauer@nz11.ukl.uni-freiburg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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