Source:http://linkedlifedata.com/resource/pubmed/id/11755477
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2001-12-28
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| pubmed:abstractText |
To assess the use of fasting plasma glucose (FPG) alone for the screening of diabetes as defined by a 2-h plasma glucose (2-h PG) > or =11.1 mmol/l following a 75-g oral glucose tolerance test, we collated the results from 17512 subjects aged 30-89 years without a previous history of diabetes from 12 general population-based Asian studies. The performance of FPG corresponding to the 2-h PG > or =11.1 mmol/l was characterized. The prevalence of diabetes was 4.0% by the FPG criteria only and 6.0% by the 2-h PG criteria only. The FPG value of 7.0 mmol/l gave a sensitivity for diabetes as defined by a 2-h PG > or =11.1 mmol/l of 46% and specificity of 99%. The FPG associated with a 2-h PG > or =11.1 mmol/l with optimal sensitivity and specificity was 5.8 mmol/l (sensitivity 79%, specificity 85%). The optimal FPG cut-point was affected by gender, age, body mass index and the presence of hypertension, and the resulting sensitivity and specificity corresponding to each optimal cut-point changed. The FPG was a specific but insensitive screening test for diabetes defined by 2-h PG > or =11.1 mmol/l. There seems to be ethnic differences with respect to optimal FPG cut-point, and different screening strategies may be necessary in different parts of the world.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0168-8227
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| pubmed:author |
pubmed-author:BalkauBeverleyB,
pubmed-author:Borch-JohnsenKnutK,
pubmed-author:Borch-JonsenKnutK,
pubmed-author:CarstensenBendixB,
pubmed-author:DECODA Study Group. Diabetes Epidemiology: Collaborative Analysis of...,
pubmed-author:International Diabetes Epidemiology Group,
pubmed-author:IwamotoYasuhikoY,
pubmed-author:NakagamiTomokoT,
pubmed-author:RYOT KTK,
pubmed-author:TajimaNaokoN,
pubmed-author:TuomilehtoJaakkoJ
|
| pubmed:issnType |
Print
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
35-43
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:11755477-Adult,
pubmed-meshheading:11755477-Aged,
pubmed-meshheading:11755477-Aged, 80 and over,
pubmed-meshheading:11755477-Blood Glucose,
pubmed-meshheading:11755477-Diabetes Mellitus, Type 2,
pubmed-meshheading:11755477-Fasting,
pubmed-meshheading:11755477-Female,
pubmed-meshheading:11755477-Glucose Tolerance Test,
pubmed-meshheading:11755477-Humans,
pubmed-meshheading:11755477-Male,
pubmed-meshheading:11755477-Middle Aged,
pubmed-meshheading:11755477-Phenotype,
pubmed-meshheading:11755477-Predictive Value of Tests,
pubmed-meshheading:11755477-Prevalence,
pubmed-meshheading:11755477-ROC Curve,
pubmed-meshheading:11755477-Sensitivity and Specificity,
pubmed-meshheading:11755477-Sex Characteristics,
pubmed-meshheading:11755477-Time Factors
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| pubmed:year |
2002
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| pubmed:articleTitle |
The fasting plasma glucose cut-point predicting a diabetic 2-h OGTT glucose level depends on the phenotype.
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| pubmed:affiliation |
nakagami@dmc.twmu.ac.jp
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|