| pubmed-article:11709186 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11709186 | lifeskim:mentions | umls-concept:C0599851 | lld:lifeskim |
| pubmed-article:11709186 | lifeskim:mentions | umls-concept:C0018670 | lld:lifeskim |
| pubmed-article:11709186 | lifeskim:mentions | umls-concept:C0037657 | lld:lifeskim |
| pubmed-article:11709186 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:11709186 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:11709186 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:11709186 | pubmed:dateCreated | 2001-11-15 | lld:pubmed |
| pubmed-article:11709186 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:abstractText | Evidence is presented for a new pathway participating in anterior neural development. It was found that IGF binding protein 5 (IGFBP-5), as well as three IGFs expressed in early embryos, promoted anterior development by increasing the head region at the expense of the trunk in mRNA-injected Xenopus embryos. A secreted dominant-negative type I IGF receptor (DN-IGFR) had the opposite effect. IGF mRNAs led to the induction of ectopic eyes and ectopic head-like structures containing brain tissue. In ectodermal explants, IGF signals induced anterior neural markers in the absence of mesoderm formation and DN-IGFR inhibited neural induction by the BMP antagonist Chordin. Thus, active IGF signals appear to be both required and sufficient for anterior neural induction in Xenopus. | lld:pubmed |
| pubmed-article:11709186 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11709186 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11709186 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11709186 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11709186 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11709186 | pubmed:issn | 1534-5807 | lld:pubmed |
| pubmed-article:11709186 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:11709186 | pubmed:author | pubmed-author:LiS YSY | lld:pubmed |
| pubmed-article:11709186 | pubmed:author | pubmed-author:WesselyOO | lld:pubmed |
| pubmed-article:11709186 | pubmed:author | pubmed-author:PeraE MEM | lld:pubmed |
| pubmed-article:11709186 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11709186 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:11709186 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11709186 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11709186 | pubmed:pagination | 655-65 | lld:pubmed |
| pubmed-article:11709186 | pubmed:dateRevised | 2007-12-11 | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:meshHeading | pubmed-meshheading:11709186... | lld:pubmed |
| pubmed-article:11709186 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11709186 | pubmed:articleTitle | Neural and head induction by insulin-like growth factor signals. | lld:pubmed |
| pubmed-article:11709186 | pubmed:affiliation | Howard Hughes Medical Institute and Department of Biological Chemistry, University of California, Los Angeles 90095, USA. | lld:pubmed |
| pubmed-article:11709186 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11709186 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11709186 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:378699 | entrezgene:pubmed | pubmed-article:11709186 | lld:entrezgene |
| entrez-gene:398022 | entrezgene:pubmed | pubmed-article:11709186 | lld:entrezgene |
| entrez-gene:398245 | entrezgene:pubmed | pubmed-article:11709186 | lld:entrezgene |
| entrez-gene:399201 | entrezgene:pubmed | pubmed-article:11709186 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11709186 | lld:pubmed |
