Linked Life Data

11603269

Source:http://linkedlifedata.com/resource/pubmed/id/11603269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
25 Pt 1
pubmed:dateCreated
2001-10-17
pubmed:abstractText
A LEADING CAUSE OF MORTALITY: Inhalation of fungal spores may cause infection and/or inflammation, which is dependent on the nature of the fungus as well as the individual's immune status. Aspergillus fumigatus is responsible for a dramatic pathology, invasive aspergillosis (IA). IA has become a leading cause of death, mainly among bone marrow transplantation or solid-organ recipients, but also among AIDS patients. IMMUNE RESPONSE: The diversity of immune failure suggests that many lines of immunity are implicated in the A. fumigatus elimination process. Non specific immunity plays a major role in the defence against A. fumigatus, including three major lines: anatomical barriers, humoral components, phagocytic cells. But acquired immunity plays a role with different T-cell subsets and their associated cytokines. FUNGUS-HOST RELATIONSHIPS: The relationship between the fungus and its host is complex and could be again study to improve the prevention and the treatment of IA. The aim of this review is a synthesis of the knowledge about the immunity response against Aspergillus fumigatus in IA.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0755-4982
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1258-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Role of local immunity in invasive pulmonary aspergillosis].
pubmed:affiliation
Laboratoire Interactions cellulaires Parasites-Hôte EA-2940, Faculté de Médecine-Pharmacie, Université Joseph Fourier, Grenoble I, La Tronche. Delphine.Aldebert@ujf-grenoble.fr
pubmed:publicationType
Journal Article, English Abstract