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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2001-10-9
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pubmed:abstractText |
The retinoblastoma-interacting zinc-finger gene RIZ is expressed in two forms (RIZ1 and RIZ2) that differ for the presence near the N-terminus of RIZ1 of a conserved domain, defined PR (PRDI-BF1-RIZ homology), homologous to a similar domain present in other proteins recognized as tumor suppressor gene products. The RIZ1 form is usually absent or expressed at low levels in tumor cells, whereas RIZ2 is frequently expressed. We investigated a possible involvement of RIZ1 in differentiation control using a myeloid cell maturation model that is easily modulated by retinoids and other agents.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Monophosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Benzoates,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Histone-Lysine N-Methyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PRDM2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Retinoblastoma Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Retinoids,
http://linkedlifedata.com/resource/pubmed/chemical/SR 11237,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tretinoin
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1076-1551
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pubmed:author |
pubmed-author:AbbondanzaCC,
pubmed-author:ArmettaII,
pubmed-author:BontempsTT,
pubmed-author:De SimoneMM,
pubmed-author:GazzerroPP,
pubmed-author:MediciNN,
pubmed-author:MolinariA MAM,
pubmed-author:MoncharmontBB,
pubmed-author:NolaEE,
pubmed-author:PucaG AGA,
pubmed-author:SchiavoneE MEM
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
552-60
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11591891-Adenosine Monophosphate,
pubmed-meshheading:11591891-Adenoviridae,
pubmed-meshheading:11591891-Antineoplastic Agents,
pubmed-meshheading:11591891-Benzoates,
pubmed-meshheading:11591891-Cell Differentiation,
pubmed-meshheading:11591891-Cells, Cultured,
pubmed-meshheading:11591891-DNA-Binding Proteins,
pubmed-meshheading:11591891-Histone-Lysine N-Methyltransferase,
pubmed-meshheading:11591891-Humans,
pubmed-meshheading:11591891-Immunoblotting,
pubmed-meshheading:11591891-Immunohistochemistry,
pubmed-meshheading:11591891-Myeloid Cells,
pubmed-meshheading:11591891-Nuclear Proteins,
pubmed-meshheading:11591891-Retinoblastoma Protein,
pubmed-meshheading:11591891-Retinoids,
pubmed-meshheading:11591891-Transcription Factors,
pubmed-meshheading:11591891-Tretinoin,
pubmed-meshheading:11591891-Zinc Fingers
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pubmed:year |
2001
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pubmed:articleTitle |
Differentiation of myeloid cell lines correlates with a selective expression of RIZ protein.
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pubmed:affiliation |
Istituto di Patologia generale ed Oncologia, Seconda Università degli studi di Napoli, Naples, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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