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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2001-10-4
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pubmed:abstractText |
Previous studies have shown that a profound suppression of immune function transiently occurs in patients who undergo surgery under general anesthesia. The decline in the absolute counts of peripheral blood lymphocytes constitutes a major factor accounting for this immune defect, and recent evidence indicates that apoptosis plays a crucial role in determining postsurgical lymphocytopenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-0010
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1190-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11585514-Anesthesia, General,
pubmed-meshheading:11585514-Apoptosis,
pubmed-meshheading:11585514-Female,
pubmed-meshheading:11585514-Flow Cytometry,
pubmed-meshheading:11585514-Glutathione,
pubmed-meshheading:11585514-Histocytochemistry,
pubmed-meshheading:11585514-Humans,
pubmed-meshheading:11585514-Lymphocytes,
pubmed-meshheading:11585514-Male,
pubmed-meshheading:11585514-Membrane Potentials,
pubmed-meshheading:11585514-Middle Aged,
pubmed-meshheading:11585514-Mitochondria,
pubmed-meshheading:11585514-Oxidation-Reduction,
pubmed-meshheading:11585514-Oxidative Stress,
pubmed-meshheading:11585514-Prospective Studies,
pubmed-meshheading:11585514-Reactive Oxygen Species,
pubmed-meshheading:11585514-Surgical Procedures, Operative
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pubmed:year |
2001
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pubmed:articleTitle |
Mitochondrial perturbations and oxidant stress in lymphocytes from patients undergoing surgery and general anesthesia.
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pubmed:affiliation |
Institute of Anesthesia and Intensive Care, Policlinico Umberto I, "La Sapienza" University, 00161 Rome, Italy. giovanna.delogu@uniroma1.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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