Linked Life Data

1154997

Source:http://linkedlifedata.com/resource/pubmed/id/1154997

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-11-7
pubmed:abstractText
The development of the lymphoid tissues in a macropod marsupial is described. The liver is the only functional haemopoietic tissue at birth. Large lymphocytes first appear in the cervical thymus at 2 days, and in the thoracic thymus at 4 days after birth. Small lymphocytes appear 1-2 days later. The histological development of the two glands is similar, but the thoracic thymus develops much more slowly than the cervical. The appearance of Hassall's corpuscles in both thymus glands correlates with the onset of humoral immune responses in this animal. Lymph nodes first appear as aggregates of lymphocytes around the lymphatic vessels at 5 days, differentiate into cortex and medulla at about 14 days, but do not develop germinal centres until about 90 days. Small lymphocytes are not observed in the spleen until the 2nd week, and reactive centres do not appear until after 90 days of pouch life. Peyer's patches are not found until 60 days of age. Large lymphocytes are seen in the bone marrow at 14 days, but small lymphocytes are not found until the 1st month. Although the sequence of lymphoid development is similar to that seen in other animals, the rapidly with which it becomes functional suggests that it is an adaptive response to early contact with environment pathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-5180
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
594-611
pubmed:dateRevised
2007-7-2
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Development of lymphoid tissue in a marsupial, Setonix brachyurus (quokka).
pubmed:publicationType
Journal Article