Linked Life Data

11541602

Source:http://linkedlifedata.com/resource/pubmed/id/11541602

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-8
pubmed:dateCreated
1999-5-10
pubmed:abstractText
The present study reports data on respiratory function of lung and chest wall following the 180 days long European - Russian EuroMir '95 space mission. Data reported refer to two subjects studied before the mission, on day 9 and 175 in flight and on days 1, 10, 12, 27 and 120 after return. In-flight vital capacity (VC) and expiratory reserve volume (ERV) were similar to those in supine posture, namely approximately 5% and approximately 30% less than in sitting posture. On day 1 after return, VC was reduced by approximately 30% in both postures. This reflected a decrease in ERV (approximately 0.5 L) and in IC (inspiratory capacity, approximately 1.7 L) that could be attributed to a marked weakening of the respiratory muscles. Regain of normal preflight values barely occurred 120 days after return. Post-flight pressure-volume curves of the lung, chest wall and total respiratory system are equal to preflight ones. The pressure-volume curve of the lung in supine posture is displaced to the right relative to sitting posture and shows a lower compliance. As far as the lung in-flight condition resembles that occurring in supine posture, this implies a lower compliance, a greater amount of blood in the pulmonary microvascular bed, a more homogeneous lung perfusion and therefore a greater microvascular filtration rate towards lung interstitium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
S
pubmed:status
MEDLINE
pubmed:issn
0094-5765
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NASA
pubmed:authorsComplete
Y
pubmed:pagination
185-204
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Respiratory mechanics after 180 days space mission (EUROMIR'95).
pubmed:affiliation
Istituto di Fisiologia Umana, Universita degli Studi di Milano, Italy. Daniele.Venturoli@unimi.it
pubmed:publicationType
Journal Article, Comparative Study