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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2001-8-6
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pubmed:abstractText |
2-18% of ductal carcinoma-No Special Type (NST) are reported to express basal cell keratin 14 and such tumours may have a different metastatic pattern and prognosis. We performed immunohistochemistry for cytokeratins 19 (luminal) and 14 (basal) on 92 ductal carcinoma-NST. Those tumours showing CK14 expression were further characterized by immunohistochemistry for myoepithelial cell phenotype and analysed by comparative genomic hybridization. The 7 cases of ductal carcinoma-NST exhibiting a basal cell phenotype were all grade III tumours and showed a molecular cytogenetic profile similar to more conventional myoepithelial cell carcinomas. Therefore it appears that grade III invasive ductal carcinomas contain a subset of tumours with specific morphological and cytogenetic characteristics, and probably prognosis for the patient.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10197608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10534158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10592056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10629549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10629552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10680887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10879734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-10963602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-11265171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-1700618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-1705754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-1709559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2175246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2178287,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2417682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2423579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2453676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2456993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-2828217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-6290045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-6301299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-7538149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-8912543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9155518,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9205858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9258662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9523192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9565338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9737789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9743305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11487275-9927758
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-0920
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 Cancer Research Campaign.
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
422-7
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pubmed:dateRevised |
2010-9-14
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pubmed:meshHeading |
pubmed-meshheading:11487275-Adult,
pubmed-meshheading:11487275-Aged,
pubmed-meshheading:11487275-Aged, 80 and over,
pubmed-meshheading:11487275-Breast Neoplasms,
pubmed-meshheading:11487275-Carcinoma, Basal Cell,
pubmed-meshheading:11487275-Carcinoma, Ductal, Breast,
pubmed-meshheading:11487275-Cell Differentiation,
pubmed-meshheading:11487275-Humans,
pubmed-meshheading:11487275-Immunoenzyme Techniques,
pubmed-meshheading:11487275-Keratins,
pubmed-meshheading:11487275-Male,
pubmed-meshheading:11487275-Middle Aged,
pubmed-meshheading:11487275-Myoepithelioma,
pubmed-meshheading:11487275-Neoplasm Proteins,
pubmed-meshheading:11487275-Neoplasm Staging,
pubmed-meshheading:11487275-Nucleic Acid Hybridization,
pubmed-meshheading:11487275-Prognosis,
pubmed-meshheading:11487275-Tumor Markers, Biological
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pubmed:year |
2001
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pubmed:articleTitle |
CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation.
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pubmed:affiliation |
The Ludwig Institute for Cancer Research/UCL Breast Molecular Pathology Group, Royal Free & University College Medical School, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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