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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2001-7-24
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pubmed:abstractText |
Platelet deposition and aggregation are central to the pathogenesis of ischemic complications of acute coronary syndromes (ACS). Pharmacodynamic effects of the platelet glycoprotein IIb/IIIa antagonist eptifibatide have been delineated in healthy subjects but not in patients with ACS. We assessed effects of eptifibatide on ex vivo platelet aggregation in patients enrolled in the Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin (eptifibatide) Therapy (PURSUIT) trial of ACS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Diphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acid Chloromethyl Ketones,
http://linkedlifedata.com/resource/pubmed/chemical/Antithrombins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIIb-IIIa...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Thrombin,
http://linkedlifedata.com/resource/pubmed/chemical/eptifibatide,
http://linkedlifedata.com/resource/pubmed/chemical/phenylalanyl-prolyl-arginine-chlorom...,
http://linkedlifedata.com/resource/pubmed/chemical/thrombin receptor peptide (42-47)
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:EisenbergP RPR,
pubmed-author:GretlerDD,
pubmed-author:HarringtonR ARA,
pubmed-author:JenningsL KLK,
pubmed-author:JosephD MDM,
pubmed-author:KleimanN SNS,
pubmed-author:LabinazMM,
pubmed-author:LincoffA MAM,
pubmed-author:McDougalM FMF,
pubmed-author:PERIGEE Investigators,
pubmed-author:PotthoffR FRF,
pubmed-author:TardiffB EBE,
pubmed-author:VorchheimerD ADA
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
399-405
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11468200-Adenosine Diphosphate,
pubmed-meshheading:11468200-Aged,
pubmed-meshheading:11468200-Amino Acid Chloromethyl Ketones,
pubmed-meshheading:11468200-Angina, Unstable,
pubmed-meshheading:11468200-Antithrombins,
pubmed-meshheading:11468200-Coronary Disease,
pubmed-meshheading:11468200-Female,
pubmed-meshheading:11468200-Humans,
pubmed-meshheading:11468200-Male,
pubmed-meshheading:11468200-Middle Aged,
pubmed-meshheading:11468200-Peptide Fragments,
pubmed-meshheading:11468200-Peptides,
pubmed-meshheading:11468200-Platelet Aggregation,
pubmed-meshheading:11468200-Platelet Aggregation Inhibitors,
pubmed-meshheading:11468200-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:11468200-Receptors, Thrombin,
pubmed-meshheading:11468200-Time Factors
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pubmed:year |
2001
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pubmed:articleTitle |
Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT.
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pubmed:affiliation |
Duke Clinical Research Institute, Durham, NC, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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