|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010031,
umls-concept:C0017337,
umls-concept:C0036945,
umls-concept:C0038952,
umls-concept:C0085295,
umls-concept:C0348011,
umls-concept:C0450127,
umls-concept:C0679058,
umls-concept:C1547699,
umls-concept:C1705822,
umls-concept:C2348480,
umls-concept:C2700640
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|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2001-6-13
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|
pubmed:abstractText |
Modification of a donor cornea by gene therapy ex vivo has potential to modulate irreversible rejection, the major cause of corneal graft failure. Our aim was to transfer the gene encoding mammalian IL-10 to ovine donor corneas and to determine subsequent orthotopic corneal allograft survival in an outbred sheep model.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
|
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pubmed:issn |
0041-1337
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
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pubmed:volume |
71
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1214-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11397952-Animals,
pubmed-meshheading:11397952-Corneal Transplantation,
pubmed-meshheading:11397952-Endothelium, Corneal,
pubmed-meshheading:11397952-Gene Transfer Techniques,
pubmed-meshheading:11397952-Genes, Reporter,
pubmed-meshheading:11397952-Graft Rejection,
pubmed-meshheading:11397952-Graft Survival,
pubmed-meshheading:11397952-Interleukin-10,
pubmed-meshheading:11397952-RNA, Messenger,
pubmed-meshheading:11397952-Sheep,
pubmed-meshheading:11397952-Transplantation, Homologous
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
Prolongation of sheep corneal allograft survival by ex vivo transfer of the gene encoding interleukin-10.
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pubmed:affiliation |
Department of Ophthalmology, Flinders University, Adelaide, South Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
