PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model.

Source:http://linkedlifedata.com/resource/pubmed/id/11230180

Hum. Mol. Genet. 2001 Mar 15 10 6 605-16

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11230180