Linked Life Data

11189730

Source:http://linkedlifedata.com/resource/pubmed/id/11189730

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-1-12
pubmed:abstractText
New variant Creutzfeldt-Jakob disease (nvCJD) is a novel human transmissible spongiform encephalopathy which was first identified in 1996 in the United Kingdom (UK). Subsequent scientific studies have revealed that the strain of the transmissible agent responsible for nvCJD is identical to that of the bovine spongiform encephalopathy (BSE) agent, and the disease has been considered as 'human BSE'. By 31 December 1999, 52 cases of nvCJD had been reported (49 cases in the UK, two cases in France and one case in the Republic of Ireland). All these individuals were under 53 years of age and all those tested were methionine homozygotes at codon 129 of the prion protein gene. The number of cases of nvCJD likely to occur in the future is impossible to estimate because of multiple uncertainties, in particular the disease incubation period, the degree of exposure to the infective agent and the susceptibility of other genetic subtypes. Continued surveillance of both BSE and CJD is required in the UK and in other countries, to ensure that the scale of this potential epidemic is adequately monitored and that all possible steps are taken to prevent further human exposure to the BSE agent.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0253-1933
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
98-120
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
The new variant of Creutzfeldt-Jakob disease.
pubmed:affiliation
Department of Clinical Neurology, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, United Kingdom.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't