Linked Life Data

11180808

Source:http://linkedlifedata.com/resource/pubmed/id/11180808

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2001-2-22
pubmed:databankReference
pubmed:abstractText
Cbfa1, a transcription factor of the runt family, was recently shown to be a key regulator in skeletal development in mammals. In the present study, we identified the cbfa1 gene from the medaka, Oryzias latipes. The amino acid sequence, including the runt domain, is highly conserved with that of mammalian cbfa1. Whole mount in situ hybridization showed that the medaka cbfa1 was expressed prominently in immature osteoblasts and chondrocytes of the developing skeletal structures during embryogenesis. The expression pattern suggests functional and evolutionary implications of the cbfa1 gene in chondrocyte differentiation between teleosts and mammals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0949-944X
pubmed:author
pubmed:issnType
Print
pubmed:volume
210
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
570-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Temporal and spatial patterns of cbfal expression during embryonic development in the teleost, Oryzias latipes.
pubmed:affiliation
Department of Life Science, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't