Source:http://linkedlifedata.com/resource/pubmed/id/11170682
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
Five new sesquiterpenes (1-5) having a carbonimidic dichloride or an aldehyde function have been isolated, together with seven known related compounds (6-12), from the sponge Stylotella aurantium. The structures of the new compounds were elucidated from spectral data. The absolute stereochemistry of the previously reported reticulidin A (10) was determined. Four of the new compounds showed cytotoxicity with a range of IC(50) values of 0.1-1 microg/mL against several tumor cell lines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11170682-Animals,
pubmed-meshheading:11170682-Antineoplastic Agents,
pubmed-meshheading:11170682-Chromatography, Thin Layer,
pubmed-meshheading:11170682-Drug Screening Assays, Antitumor,
pubmed-meshheading:11170682-Humans,
pubmed-meshheading:11170682-Mass Spectrometry,
pubmed-meshheading:11170682-Porifera,
pubmed-meshheading:11170682-Sesquiterpenes,
pubmed-meshheading:11170682-Spectrophotometry, Infrared,
pubmed-meshheading:11170682-Spectrophotometry, Ultraviolet,
pubmed-meshheading:11170682-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
New sesquiterpene carbonimidic dichlorides and related compounds from the sponge Stylotella aurantium.
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pubmed:affiliation |
Department of Chemistry, Biology, and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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