Source:http://linkedlifedata.com/resource/pubmed/id/11164394
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2001-2-22
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| pubmed:abstractText |
We studied 43 patients with blunt trauma (injury severity score, > or =25), age >14 years and length of the intensive care unit (ICU) stay >48 h in order to estimate the frequency of sepsis and to identify early risk factors related to its development. Clinical data were collected during the first 24 h and several inflammatory mediators were determined from serum samples of the first 2 days after injury.Twenty-one patients (48.8%) met sepsis criteria during their ICU stay, 9 (20.9%) fulfilled only criteria for sepsis; 6 (13.9%) fulfilled criteria for severe sepsis and another 6 (13.9%) criteria for septic shock. An APACHE II score > or =14, the presence of hypovolemic shock, the need for three or more units of blood to be transfused and the administration of a total volume of fluids > or =10 l were all factors associated significantly with the development of sepsis. In the multivariant analysis, the need for a total volume of fluids > or =10 l was the only independent risk factor (adjusted odds ratio=10.49, 95% CI, 2.34-47.02; P=0.002). No significant differences were documented in relation to the behaviour of the serum markers.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
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| pubmed:issn |
0020-1383
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
32
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
5-12
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| pubmed:dateRevised |
2009-11-3
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| pubmed:meshHeading |
pubmed-meshheading:11164394-Adult,
pubmed-meshheading:11164394-Blood Transfusion,
pubmed-meshheading:11164394-Female,
pubmed-meshheading:11164394-Fluid Therapy,
pubmed-meshheading:11164394-Humans,
pubmed-meshheading:11164394-Inflammation Mediators,
pubmed-meshheading:11164394-Injury Severity Score,
pubmed-meshheading:11164394-Intensive Care,
pubmed-meshheading:11164394-Length of Stay,
pubmed-meshheading:11164394-Male,
pubmed-meshheading:11164394-Middle Aged,
pubmed-meshheading:11164394-Multivariate Analysis,
pubmed-meshheading:11164394-Risk Factors,
pubmed-meshheading:11164394-Sepsis,
pubmed-meshheading:11164394-Wounds, Nonpenetrating
|
| pubmed:year |
2001
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| pubmed:articleTitle |
Early risk factors for sepsis in patients with severe blunt trauma.
|
| pubmed:affiliation |
Department of Critical Care and Emergency Medicine, Servicio de Cuidados Críticos y Urgencias (UCI-HRT), Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot s/n, 41013, Sevilla, Spain.
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| pubmed:publicationType |
Journal Article
|