Linked Life Data

1115764

Source:http://linkedlifedata.com/resource/pubmed/id/1115764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1975-6-2
pubmed:abstractText
High molecular weight poly(L-porlyl-L-alpha-phenylglycyl-L-proline) was synthesized by condensation of L-prolyl-L-alpha-phenylglycyl-L-proline pentachlorophenyl ester in N,N-dimethylformamide. The solution properties of this material have been investigated by circular dichroism and 220-MHz nuclear magnetic resonance spectroscopy in solvents such as trifluoroethanol (F3EtOH), chloroform, trifluoroacetic acid (F3CCOOH), chloroform-F3CCOOH and F3EtOH-F3CCOOH mixtures. Ordered structures can be formed in F3EtOH and chloroform, which we believe to be similar to the poly-L-proline II form. The ordered form easily undergoes a conformational transition to an unordered form upon addition of small amounts of F3CCOOH to the chloroform solution. The ordered structure is not disrupted upon addition of 12 per cent F3CCOOH to a F3EtOH solution of the polypeptide.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-2960
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
485-91
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Synthesis and conformational studies in solution of sequential copolypeptides: poly(L-prolyl-L-alpha-phenylglycyl-L-proline).
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.