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rdf:type |
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lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0015127,
umls-concept:C0028754,
umls-concept:C0030956,
umls-concept:C0034693,
umls-concept:C0043096,
umls-concept:C0179636,
umls-concept:C0205191,
umls-concept:C1314792,
umls-concept:C1824528,
umls-concept:C2700303,
umls-concept:C2709063
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pubmed:issue |
8
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|
pubmed:dateCreated |
2001-1-11
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|
pubmed:abstractText |
Hypothalamic neuropeptide CART (cocaine-amphetamine-regulated transcript) is a leptin-dependent endogenous satiety factor in the rat, and single central injections of recombinant CART(42-89) lowers food intake in rats and mice. To assess the potential role of CART as a long-term regulator of food intake, we investigated the effects of continuous infusion of recombinant CART(42-89) on food consumption and body weight.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1071-7323
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
590-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11156435-Animals,
pubmed-meshheading:11156435-Appetite Regulation,
pubmed-meshheading:11156435-Body Weight,
pubmed-meshheading:11156435-Dose-Response Relationship, Drug,
pubmed-meshheading:11156435-Eating,
pubmed-meshheading:11156435-Infusion Pumps, Implantable,
pubmed-meshheading:11156435-Lateral Ventricles,
pubmed-meshheading:11156435-Male,
pubmed-meshheading:11156435-Motor Activity,
pubmed-meshheading:11156435-Nerve Tissue Proteins,
pubmed-meshheading:11156435-Rats,
pubmed-meshheading:11156435-Rats, Sprague-Dawley,
pubmed-meshheading:11156435-Rats, Zucker,
pubmed-meshheading:11156435-Time Factors,
pubmed-meshheading:11156435-Weight Loss
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pubmed:year |
2000
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pubmed:articleTitle |
Chronic intracerebroventricular administration of recombinant CART(42-89) peptide inhibits and causes weight loss in lean and obese Zucker (fa/fa) rats.
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pubmed:affiliation |
Department of Anatomy, University of Copenhagen, Denmark. PJL@dadlnet.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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