Source:http://linkedlifedata.com/resource/pubmed/id/11102776
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2000-12-11
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pubmed:abstractText |
The application of self-antigens as therapeutic tools is validated in inbred animal models of autoimmune disease. Mechanisms of antigen-induced tolerance (apoptosis, anergy, regulatory T cells and immune deviation) are being clarified in relation to the properties of antigens and the modes and routes of their delivery. Mucosa-mediated tolerance remains the predominant mode of antigen-specific therapy but awaits demonstration of clinical efficacy in human autoimmune disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0952-7915
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
704-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11102776-Animals,
pubmed-meshheading:11102776-Autoantigens,
pubmed-meshheading:11102776-Autoimmune Diseases,
pubmed-meshheading:11102776-Cytokines,
pubmed-meshheading:11102776-Humans,
pubmed-meshheading:11102776-Immune Tolerance,
pubmed-meshheading:11102776-Immunotherapy,
pubmed-meshheading:11102776-Mucous Membrane,
pubmed-meshheading:11102776-T-Lymphocytes
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pubmed:year |
2000
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pubmed:articleTitle |
Antigen-specific therapy for autoimmune disease.
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pubmed:affiliation |
Autoimmunity and Transplantation Division, The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville 3050, Australia. harrison@wehi.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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