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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1976-3-15
|
| pubmed:abstractText |
The effects of isoprenaline and adrenalin on the myocardial contractility of transplanted heart were studied in 6 mongrel dogs which had undergone orthotopic cardiac transplantation. Isoprenaline and adrenaline produced a fall in end-diastolic and end-systolic volumes, and an increase in stroke volume, cardiac output and velocity of contraction when the heart rate was increased. Similar changes were observed in 4 mongrel dogs tested as controls, with the exception of a less pronounced increase of cardiac output after administration of isoprenaline and adrenalin and a fall in stroke volume associated with a higher acceleration of heart rate after administration of isoprenaline. These minor differences between the transplanted and intact heart were thought to be a reflexion of the increased blood volume following heart transplantation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0036-5580
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
175-80
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1108180-Animals,
pubmed-meshheading:1108180-Blood Pressure,
pubmed-meshheading:1108180-Cardiac Output,
pubmed-meshheading:1108180-Dogs,
pubmed-meshheading:1108180-Epinephrine,
pubmed-meshheading:1108180-Heart Rate,
pubmed-meshheading:1108180-Heart Transplantation,
pubmed-meshheading:1108180-Isoproterenol,
pubmed-meshheading:1108180-Myocardial Contraction,
pubmed-meshheading:1108180-Transplantation, Homologous
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
The effects of beta-adrenergic agents on the contractility of transplanted canine heart.
|
| pubmed:publicationType |
Journal Article
|