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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2000-10-12
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pubmed:abstractText |
To formulate aqueous eye drops containing methazolamide 1% in cyclodextrin solution and to evaluate their effect on intraocular pressure (IOP) in a double-blind randomized trial in humans. Methazolamide, a carbonic anhydrase inhibitor (CAI), has been used in oral doses in the treatment of glaucoma but hitherto has not been successfully formulated in eye drops. In this study the effects of methazolamide are compared with those of dorzolamide (Trusopt).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3552-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11006251-Carbonic Anhydrase Inhibitors,
pubmed-meshheading:11006251-Cyclodextrins,
pubmed-meshheading:11006251-Double-Blind Method,
pubmed-meshheading:11006251-Female,
pubmed-meshheading:11006251-Humans,
pubmed-meshheading:11006251-Intraocular Pressure,
pubmed-meshheading:11006251-Male,
pubmed-meshheading:11006251-Methazolamide,
pubmed-meshheading:11006251-Ocular Hypertension,
pubmed-meshheading:11006251-Ophthalmic Solutions,
pubmed-meshheading:11006251-Pharmaceutical Vehicles,
pubmed-meshheading:11006251-Sulfonamides,
pubmed-meshheading:11006251-Thiophenes
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pubmed:year |
2000
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pubmed:articleTitle |
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
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pubmed:affiliation |
Departments of Ophthalmology and. Pharmacy, University of Iceland, Reykjavík.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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