10873558

Source:http://linkedlifedata.com/resource/pubmed/id/10873558

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017262, umls-concept:C0020792, umls-concept:C0086418, umls-concept:C0185117, umls-concept:C1333585, umls-concept:C1517495, umls-concept:C2911684
pubmed:issue	1
pubmed:dateCreated	2000-7-27
pubmed:databankReference	http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AJ272427
pubmed:abstractText	We report the identification, genomic structure, chromosomal localization, and expression analysis of human frizzled-3 (FZD3), a 7-transmembrane receptor belonging to the frizzled family. The cDNA obtained from adult human brain shows 91% identity at the nucleotide level and 98% at the amino acid level to mouse frizzled-3 (fzd3). The FZD3 locus is located on chromosome 8p21, spans 48 Kb and its coding sequence is distributed in 6 exons intercalated by 5 introns. FZD3 is expressed in all analyzed human tissues, with quantitatively higher expression in the CNS and in urogenital structures.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372516
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/FZD3 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Frizzled Receptors, http://linkedlifedata.com/resource/pubmed/chemical/Fzd3 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0006-291X
pubmed:author	pubmed-author:CaricasoleAA, pubmed-author:FormentiEE, pubmed-author:SahaA LAL, pubmed-author:TerstappenG CGC
pubmed:copyrightInfo	Copyright 2000 Academic Press.
pubmed:issnType	Print
pubmed:day	24
pubmed:volume	273
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	27-34
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:10873558-Amino Acid Sequence, pubmed-meshheading:10873558-Animals, pubmed-meshheading:10873558-Base Sequence, pubmed-meshheading:10873558-Brain, pubmed-meshheading:10873558-Chromosomes, Human, Pair 8, pubmed-meshheading:10873558-Cloning, Molecular, pubmed-meshheading:10873558-Exons, pubmed-meshheading:10873558-Frizzled Receptors, pubmed-meshheading:10873558-Gene Expression Profiling, pubmed-meshheading:10873558-Humans, pubmed-meshheading:10873558-Introns, pubmed-meshheading:10873558-Mice, pubmed-meshheading:10873558-Molecular Sequence Data, pubmed-meshheading:10873558-Neuroblastoma, pubmed-meshheading:10873558-Organ Specificity, pubmed-meshheading:10873558-Physical Chromosome Mapping, pubmed-meshheading:10873558-RNA, Messenger, pubmed-meshheading:10873558-Receptors, Cell Surface, pubmed-meshheading:10873558-Receptors, G-Protein-Coupled, pubmed-meshheading:10873558-Sequence Alignment, pubmed-meshheading:10873558-Sequence Homology, pubmed-meshheading:10873558-Tumor Cells, Cultured
pubmed:year	2000
pubmed:articleTitle	Identification, gene structure, and expression of human frizzled-3 (FZD3).
pubmed:affiliation	Molecular Biology and Biochemistry Unit, Biology Department, GlaxoWellcome Medicines Research Centre, Via Fleming, 4, Verona, 37135, Italy.
pubmed:publicationType	Journal Article