pubmed-article:10833436 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10833436 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
pubmed-article:10833436 | lifeskim:mentions | umls-concept:C0906203 | lld:lifeskim |
pubmed-article:10833436 | lifeskim:mentions | umls-concept:C0754530 | lld:lifeskim |
pubmed-article:10833436 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:10833436 | pubmed:dateCreated | 2000-7-10 | lld:pubmed |
pubmed-article:10833436 | pubmed:abstractText | Vesl-1S/Homer 1a, reported originally as Vesl/Homer, was isolated as a synaptic plasticity-regulated gene. The expression of Vesl-1S/Homer 1a is regulated during long-term potentiation in the hippocampus. Vesl-1L/Homer 1c, which appears to be formed by a splicing event, shares the N-terminus with Vesl-1S/Homer 1a and also contains additional amino acids at the C-terminus. The short form and the long form of the family members both interact with group 1 metabotropic glutamate receptors (mGluRs). We herein report the identification of syntaxin 13 as a molecule that interacts with Vesl-1L using yeast two-hybrid screening. Syntaxin 13 is a member of the syntaxin family and is regarded as soluble N-ethylmaleimide-sensitive attachment proteins receptors (SNAREs) in the endosomal membranes. The interaction of Vesl-1L and syntaxin 13 was biochemically confirmed by in vitro binding assays. The coexpression of the two proteins in the transfected cells resulted in a colocalization in the intracellular vesicle-like structures. We thus propose that the association of Vesl-1L with syntaxin 13 plays a role in the translocation of Vesl-1L to the intracellular organelles. | lld:pubmed |
pubmed-article:10833436 | pubmed:language | eng | lld:pubmed |
pubmed-article:10833436 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10833436 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:10833436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10833436 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10833436 | pubmed:month | Jun | lld:pubmed |
pubmed-article:10833436 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:10833436 | pubmed:author | pubmed-author:KatzLL | lld:pubmed |
pubmed-article:10833436 | pubmed:author | pubmed-author:SugiyamaHH | lld:pubmed |
pubmed-article:10833436 | pubmed:author | pubmed-author:MinakamiRR | lld:pubmed |
pubmed-article:10833436 | pubmed:copyrightInfo | Copyright 2000 Academic Press. | lld:pubmed |
pubmed-article:10833436 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10833436 | pubmed:day | 7 | lld:pubmed |
pubmed-article:10833436 | pubmed:volume | 272 | lld:pubmed |
pubmed-article:10833436 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10833436 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10833436 | pubmed:pagination | 466-71 | lld:pubmed |
pubmed-article:10833436 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
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pubmed-article:10833436 | pubmed:year | 2000 | lld:pubmed |
pubmed-article:10833436 | pubmed:articleTitle | Interaction of Vesl-1L/Homer 1c with syntaxin 13. | lld:pubmed |
pubmed-article:10833436 | pubmed:affiliation | School of Health Sciences, Kyushu University, Fukuoka, Japan. | lld:pubmed |
pubmed-article:10833436 | pubmed:publicationType | Journal Article | lld:pubmed |
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