Source:http://linkedlifedata.com/resource/pubmed/id/10733161
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-6-12
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pubmed:abstractText |
An epidemiological survey of Trypanosoma cruzi infection was carried out in Bodocó, located in the western part of the State of Pernambuco, Brazil. Two hundred and forty-one individuals were parasitologically and immunologically screened. Although hemoculture did not reveal the presence of parasites in the blood, the sera of 5 individuals were scored as positive by the indirect fluorescence antibody test and the enzyme-linked immunosorbent assay. Seropositivity in individuals above and below the age of 40 was 14.8 and 0.5%, respectively. These results indicate that recent infections with T. cruzi are rare in this area. However, since a T. cruzi-infected triatomid (Triatoma brasiliensis) was captured in a school classroom, this area must be considered endemic. When triatomid feces containing parasites were inoculated into a jird (mongolian gerbil), parasitemia appeared 10 days later. Immunohistochemical staining, using monoclonal antibody specific for T. cruzi, labeled organisms in jird tissues. These observations demonstrate that the jird is a suitable host for experimental T. cruzi infections and that monoclonal antibody is effective for detection of the parasite in host tissues.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0385-0005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10733161-Adult,
pubmed-meshheading:10733161-Animals,
pubmed-meshheading:10733161-Antibodies, Protozoan,
pubmed-meshheading:10733161-Brazil,
pubmed-meshheading:10733161-Chagas Disease,
pubmed-meshheading:10733161-Child,
pubmed-meshheading:10733161-Humans,
pubmed-meshheading:10733161-Insect Vectors,
pubmed-meshheading:10733161-Panstrongylus,
pubmed-meshheading:10733161-Population Surveillance,
pubmed-meshheading:10733161-Triatoma,
pubmed-meshheading:10733161-Trypanosoma cruzi
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pubmed:year |
1999
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pubmed:articleTitle |
Survey for Trypanosoma cruzi infection in a municipality in northeast Brazil.
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pubmed:affiliation |
Laboratório de Imunopatologia Prof. Keizo Asami, Federal Universidade de Pernambuco, Recife, Brazil. htachiba@is.icc.u-tokai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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