Source:http://linkedlifedata.com/resource/pubmed/id/10593615
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2000-1-3
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pubmed:abstractText |
Immunocytochemistry for choline acetyltransferase (ChAT), the synthesizing enzyme for acetylcholine, was used to determine the onset and to follow the maturation of the cholinergic cells in the retina of a marsupial, the South American opossum (Didelphis aurita). ChAT-immunoreactivity was first detected in amacrine cells in the ganglion cell layer by postnatal day 15 (P15) and in the inner nuclear layer by P35. Much later, at P50 a second sub-population of ChAT-immunoreactive cell bodies was evident in the inner nuclear layer. Processes from ChAT-immunoreactive amacrine cells were detected in the two bands of the inner plexiform layer before synaptogenesis. In the adult retina, these two bands correspond to sublamina 2 and 4 of the inner plexiform layer. In flat whole-mounted preparations, cholinergic cell density was 263 +/- 13 cells/mm2 in the ganglion cell layer and it was estimated a total of 24,000 cholinergic neurons. ChAT-immunoreactive somata showed a random pattern of distribution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0736-5748
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
795-804
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10593615-Age Factors,
pubmed-meshheading:10593615-Animals,
pubmed-meshheading:10593615-Antibody Specificity,
pubmed-meshheading:10593615-Cell Count,
pubmed-meshheading:10593615-Choline O-Acetyltransferase,
pubmed-meshheading:10593615-Cholinergic Fibers,
pubmed-meshheading:10593615-Opossums,
pubmed-meshheading:10593615-Retina
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pubmed:year |
1999
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pubmed:articleTitle |
Ontogeny of cholinergic amacrine cells in the oppossum (Didelphis aurita) retina.
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pubmed:affiliation |
Departamento Histologia e Embriologia, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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